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I can definitely give a few recommendations in San Francisco! I’ll try to send a few per neighborhood that I love:
NorthBeach: The Stinking Rose (garlic restaurant) or Pellegrini, both on Columbus St. My favorite wine bar here is Dell’Uva on Green!
Marina: Bin38 is a great wine bar near Chestnut, good food too! Mamacita has amazing mexican food and a great bar atmosphere!
PacHeights: Dosa has AMAZING indian food, and is in the fun Fillmore district (my neighborhood!). Also, definitely try Dino’s for really relaxed atmosphere and great pizza and beer!
SOMA: So many to choose from… great happy hour at Cosmopolitan, and Palomino on the Embarcadero! Ritzy seafood at Waterbar (pretty pricey!), and great outdoor atmosphere at Paragon. Looking for a quick lunch bite? The Great American Grilled Cheese place is CLASSIC, so delicious! Oh, and 21st Amendment is a great brewery near the ballpark as well.
Hayes Valley: STACKS. So delicious… best breakfast spot. Definitely share a huge pancake with a friend.
Haight: Little Chihuahua has some of the best mexican food in the city, in my opinion… pretty cheap too. Toronado has an awesome beer selection as far as bars go, and there is a GREAT pizza place next door that hits the spot after a few drinks!
Castro: Awesome bento boxes and bottomless mimosas at Barracuda on Market.
Mission: I’ve only been a few places in the mission, but the ones I’ve been to I’ve loved! Tokyo GoGo had awesome sushi, and we followed it with huge specialty Martinis at Blondies down the street. Heart is also a great wine bar with yummy snacks.
I hope this helps! Happy eating/drinking!